Fig. 1: Rich-club organization of structural network. | Translational Psychiatry

Fig. 1: Rich-club organization of structural network.

From: Alterations of core structural network connectome associated with suicidal ideation in major depressive disorder patients

Fig. 1: Rich-club organization of structural network.The alternative text for this image may have been generated using AI.

A Normalized and real rich club organization curves for the structural group-averaged brain network in CN (blue line), MDDSI (red line), and MDDNSI (olive line) (K > 14, P = 0.026, 5000 permutations). B Distributions of hub nodes (red nodes) in all individuals. C Description model for rich club organization. Structural connections cross individual brain network was divided into 3 distinct subtypes: rich-club (red lines) connections link rich-club members, feeder connections (yellow lines) link rich-club members to non-rich-club members, and local connections (blue lines) connect non-rich-club members. D The proportions of rich-club, feeder, and local connections in the structural group-averaged brain networks of each group. E The integrated connection strength of each sub-properties (rich-club, feeder, local) of rich club organization. Color icon as before. The error bars indicate standard deviation. *P < 0.05. CN, cognitively normal; MDDSI, major depression disorder with suicidal ideation; MDDNSI, major depression disorder with non-suicidal ideation; INS.L, left insula; INS.R, right insula; CAU.L, left caudate; CAU.R, right caudate; PUT.L, left putamen; PUT.R, left putamen; THA.L, left thalamus; THA.R, right thalamus; PCUN.L, left precuneus; PCUN.R, right precuneus; ACG.L, left anterior cingulate and paracingulate gyrus; FA, fractional anisotropy.

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