Table 3 [¹¹C]PiB SUVRs.

	Mean (SD)
	Subjects with alcohol-use disorder (n = 19)	Healthy controls (n = 20)
			95% CI	p-Value	d	Bayes factor (B₁₀)^a
SUVR
Global	1.10 (0.06)	1.10 (0.04)	(−0.02, 0.02)	0.94	0.004	4.3
Anterior cingulate	1.17 (0.10)	1.17 (0.08)	(−0.04, 0.04)	0.72	0.02	4.3
Anterior ventral striatum	1.09 (0.12)	1.11 (0.08)	(−0.05, 0.08)	0.59	0.18	3.7
Superior frontal	1.10 (0.10)	1.09 (0.07)	(−0.03, 0.03)	0.83	0.12	4.0
Orbitofrontal	1.14 (0.08)	1.13 (0.05)	(−0.03, 0.04)	0.99	0.15	3.9
Insula	1.13 (0.06)	1.12 (0.05)	(−0.04, 0.03)	0.70	0.12	4.0
Lateral temporal	1.07 (0.04)	1.07 (0.03)	(−0.02, 0.03)	0.80	0.08	4.1
Parietal	1.07 (0.05)	1.08 (0.04)	(−0.02, 0.04)	0.62	0.16	3.8
Posterior cingulate	1.16 (0.06)	1.19 (0.06)	(−0.01, 0.07)	0.09	0.55	1.2
Precuneus	1.16 (0.07)	1.18 (0.06)	(−0.02, 0.06)	0.42	0.26	3.2
SUVR, GTM-corrected
Global	1.33 (0.18)	1.26 (0.07)	(−0.02, 0.10)	0.16	0.45	1.8
Anterior cingulate	1.38 (0.22)	1.33 (0.17)	(−0.08, 0.14)	0.77	0.23	3.4
Anterior ventral striatum	0.99 (0.19)	1.02 (0.17)	(−0.08, 0.15)	0.55	0.19	3.6
Superior frontal	1.40 (0.26)	1.31 (0.12)	(−0.03, 0.14)	0.19	0.41	2.1
Orbitofrontal	1.42 (0.18)	1.37 (0.08)	(−0.05, 0.09)	0.69	0.30	2.9
Insula	1.10 (0.12)	1.06 (0.08)	(−0.03, 0.07)	0.51	0.38	2.3
Lateral temporal	1.26 (0.10)	1.22 (0.07)	(−0.09, 0.02)	0.23	0.39	2.2
Parietal	1.33 (0.20)	1.26 (0.09)	(−0.18, 0.02)	0.13	0.51	1.4
Posterior cingulate	1.23 (0.15)	1.21 (0.09)	(−0.06, 0.07)	0.81	0.12	4.0
Precuneus	1.30 (0.21)	1.22 (0.08)	(−0.04, 0.13)	0.27	0.49	1.6

^aThe likelihood ratio of observing this data under the assumption that AUD does not influence amyloid-β vs. the assumption that AUD influences amyloid-β, where B₁₀ = 1 indicates no evidence in favor of either the null or alternative hypotheses (B₁₀ = 3–10: moderate evidence that AUD does not influence amyloid-β production). For more information, see Lee and Wagenmakers⁵⁹. Calculated using “Bayesian Statistics” feature in SPSS.

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