Table 4 MRI outcomes.
Mean (SD) | |||
|---|---|---|---|
Subjects with alcohol-use disorder (n = 19) | Healthy controls (n = 20) | p-Value | |
Cortical thickness (mm) | |||
AD-signature composite | 2.6 (0.2) | 2.8 (0.1) | 0.0003 |
Entorhinal | 3.5 (0.4) | 3.7 (0.4) | 0.12 |
Inferior temporal | 2.6 (0.2) | 2.8 (0.1) | 0.01 |
Middle temporal | 2.6 (0.2) | 2.8 (0.1) | 0.0001 |
Fusiform | 2.6 (0.2) | 2.7 (0.1) | 0.002 |
Prefrontal | 2.3 (0.1) | 2.4 (0.1) | 0.01 |
Parietal | 2.0 (0.1) | 2.2 (0.1) | 0.0001 |
Occipital | 1.9 (0.1) | 2.0 (0.1) | 0.003 |
GM volumesa (unitless) | |||
Hippocampus | 26.4 (3.1) | 29.3 (2.2) | 0.002 |
Amygdala | 10.6 (1.3) | 11.5 (0.9) | 0.02 |
Thalamus | 43.0 (4.5) | 46.2 (4.3) | 0.03 |
Caudate | 22.3 (2.5) | 22.2 (2.2) | 0.83 |
Putamen | 33.7 (4.0) | 36.1 (3.6) | 0.05 |
Nucleus accumbens | 4.0 (0.7) | 4.4 (0.5) | 0.03 |
Cerebellar cortex | 296.6 (30.3) | 321.4 (31.5) | 0.02 |
