Fig. 3: NA release in the PFC and STR of VB6-deficient mice. | Translational Psychiatry

Fig. 3: NA release in the PFC and STR of VB6-deficient mice.

From: Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment

Fig. 3

Basal levels of NA in A the PFC and C the STR are shown. (n.s. using Student’s t-test. n = 7). NA release in B the PFC and D the STR were measured. High K+ stimulation was performed at the time point of 0 min (Two-way ANOVA with repeated measures: B FInteraction(8,96) = 1.95, p > 0.05; FTime(8,96) = 46.8, p < 0.001; F VB6(1,12) = 3.49, p > 0.05, D FInteraction(8,88) = 3.98, p < 0.001; FTime(8,88) = 19.1, p < 0.001; F VB6(1,11) = 3.98, p > 0.05; **p < 0.01, ***p < 0.001 using Bonferroni’s multiple comparison test. n = 7). The data were represented as the mean ± SEM values.

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