Table 1 Demographic and clinical characteristics of study patients with bipolar I (BPI) disordera.
From: Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population
Discovery group | Replication group | |||||
|---|---|---|---|---|---|---|
Onset ≤ 20 (N = 516) | Onset > 20 (N = 790) | P value | Onset ≤ 20 (N = 153) | Onset > 20 (N = 320) | P value | |
Sex | 0.843 | 0.938 | ||||
Male | 229 (44.4%) | 355 (44.9%) | 74 (48.4%) | 156 (48.7%) | ||
Female | 287 (55.6%) | 435 (55.1%) | 79 (51.6%) | 164 (51.3%) | ||
Age at onset | 17.02 ± 2.54 | 31.83 ± 9.29 | <0.001 | 17.65 ± 1.99 | 32.05 ± 9.03 | <0.001 |
Age at recruitment | 37.56 ± 11.79 | 41.84 ± 11.63 | <0.001 | 37.56 ± 12.52 | 47.23 ± 12.35 | <0.001 |
With psychotic features (%) | 465 (90.8%) | 665 (84.2%) | 0.002 | 138 (90.2%) | 259 (80.9%) | 0.010 |
With suicide attempt | 264 (51.1%) | 345 (43.7%) | 0.008 | 64 (41.8%) | 110 (34.3%) | 0.116 |
First mood episode | 0.005 | 0.685 | ||||
Mania | 283 (54.8%) | 495 (62.7%) | 92 (60.1%) | 205 (64.1%) | ||
Depression | 233 (45.2%) | 295 (37.3%) | 61 (39.9%) | 115 (35.9%) | ||
