Table 3 Baseline cohort demographics for patients with a prior psychiatric (F20–F48) diagnosis.

From: Onset and recurrence of psychiatric disorders associated with anti-hypertensive drug classes

 

CCB

Diuretic

CCB

ACEI

CCB

ARB

CCB

BB

Number

33,734

33,734

48,590

48,590

37,229

37,229

39,281

39,281

Age at index (years)

56.4 (15.0)

56.5 (14.7)

57.3 (14.8)

57.1 (13.3)

57.8 (14.1)

58.0 (12.7)

56.7 (14.2)

57.1 (14.4)

Sex (M:F %)

39: 61

38: 62

33: 67

33: 67

30: 70

31: 69

34: 66

34: 66

Race (% W, B, O)b

77, 17, 6

76, 17, 7

79, 16, 5

79, 15, 6

84, 10, 6

83, 10, 7

75, 19, 6

75, 19, 6

Blood pressure

134/79

132/78

134/78

134/79

133/77

132/78

136/80a

130/76b

Prior diuretic (%)

41

42

44

51

41

36

Prior ACEI (%)

30

34

44

35

36

28

Prior ARB (%)

12

15

28

4

18

11

Prior BB (%)

35

33

40

31

44

35

Prior other AHT (%)

14

10

16

10

16

10

12

10

Prior F20–29 (%)

6

5

6

6

6

3

6

7

Prior F30–39 (%)

65

67

66

67

68

66

67

66

Prior F40–48 (%)

64

62

64

61

63

63

62

64

Prior F10–19 (%)

25

24

24

25

28

19

25

24

Prior antidepressant (%)

59

57

60

59

63

64

60

58

Prior anxiolytic (%)

53

49

55

48

57

52

49

53

Prior antipsychotic (%)

12

10

12

10

12

7

10

12

  1. Cohorts propensity score-matched for age, sex, race, and blood pressure (most recent recorded value). “Prior” means any occurrence before the start of the exposure period.
  2. aBlood pressure could not be matched for CCB vs BB (SD = 0.31 for systolic and diastolic).
  3. bW: white. B: black or African American. O: other or not known.