Fig. 4: Alterations in the levels of IL-6 and neurotrophins (BDNF) based on gender, suicidality, and psychiatric medications.

A Brain BDNF was elevated in suicide—3 ± 203, compared to non-sucide—2 ± 129, p = 0.0023. B Brain BDNF levels without psychiatric medications were significantly lower 133 ± 93 compared to the treated subjects 212 ± 127, p = 0.005. C Brain BDNF were significantly lower 149 ± 122 in females compared to males 212 ± 121, p = 0.017. D CSF IL-6 levels were significantly higher in Females 923 ± 1246 compared to males 565 ± 915, p = 0.021.