Fig. 5: Overview of the study to understand the interlink between central nervous system and periphery in individual subjects. | Translational Psychiatry

Fig. 5: Overview of the study to understand the interlink between central nervous system and periphery in individual subjects.

From: Altered levels of interleukins and neurotrophic growth factors in mood disorders and suicidality: an analysis from periphery to central nervous system

Fig. 5

Graphical illustration of main top-down, central nervous system (CNS)–Brain/CSF to periphery, and bottom-up (periphery to CNS) communication pathways through the receptors and summary of peripheral and central pathology through interleukins—IL-6 and Il-1β and neurotrophins, BDNF, and GDNF. Factors that are associated with the analyses are suicidality, age, gender, psychiatric medications, RIN, pH, and PMI.

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