Fig. 2: Base–case scenario analysis in Japan. | Translational Psychiatry

Fig. 2: Base–case scenario analysis in Japan.

From: Cost effectiveness of pharmacogenetic-guided clozapine administration based on risk of HLA variants in Japan and the UK

Fig. 2

A Tornado plot of the one-way sensitivity analysis: The black vertical line indicates the incremental cost-effectiveness ratio (ICER) of the base-case analysis. The red vertical line indicates the cost-per QALY threshold. The numbers are the ranges used in the sensitivity analysis. The blue shaded bars represent lower parameters than those used in the base–case analysis, and the red shaded bars represent higher parameters than those used in the base-case analysis. B Scatter plot for incremental cost and effectiveness: green dots indicate ICERs within willing to pay threshold and red dots indicate out of the threshold. C Cost-effectiveness acceptability curve, CLZ clozapine, PPV positive predictive value, CIAG clozapine-induced agranulocytosis/granulocytopenia, WTP willing to pay.

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