Fig. 1: Venn diagrams of shared and unique polygenic variants. | Translational Psychiatry

Fig. 1: Venn diagrams of shared and unique polygenic variants.

From: Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes

Fig. 1

Venn diagrams of shared and unique trait-influencing variants, showing polygenic overlap (gray) between bipolar disorder (BIP) (blue) and (A) body mass index (BMI) (orange), (B) systolic blood pressure (SBP) (orange), (C) diastolic blood pressure (DBP) (orange), and (D) coronary artery disease (CAD) (orange). The numbers in the Venn diagram indicate the estimated quantity of shared and unique trait-influencing variants (in thousands), explaining 90% of SNP heritability in each phenotype, followed by standard error. The size of the circles reflects the degree of polygenicity. The figure is based on MiXeR results.

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