Fig. 2: Network-level features predicting resilience, over time relative to trauma exposure.

Across time following trauma, network patterns are noticeable. Pre-trauma findings (A) suggest that structural integrity/activation of inhibition areas in the threat and cognitive control networks positively correlate with resilience, while threat response and salience networks show negative associations with resilience. Post-trauma findings are split into two categories: early, peri-trauma findings that predict early resilience within the first year following trauma (B) and peri-trauma findings that predict later recovery and resilience years following the trauma (C). Correlations for the inhibitory and response areas of the threat network and cognitive control network are consistent over all three timepoints, and across the two post-trauma timepoints, the attention and reward networks both have positive correlations with resilience. However, some networks exhibit changes across time points. The DMN during peri-trauma negatively predicts early resilience, while it positively predicts later recovery and resilience. Changes are also seen across the salience network, with less salience activation pre-trauma predicting resilience, but higher salience activation post-trauma predicting peri-trauma resilience and later recovery. Axis values represent overall negative (purple) or overall positive (blue) correlations. Time points that do not have strong evidence supporting network correlations are indicated by grey dots.