Table 4 The characteristics of the voxel-based morphometry studies included in the meta-analyses.

From: A review of functional and structural neuroimaging studies to investigate the inner speech model of auditory verbal hallucinations in schizophrenia

Study

Software

Comparison or correlation

Whole-brain or ROI analysis

No. of hallucinators

No. of non-hallucinators

Stereotaxic space

Shapleske et al. [30] (2002)

Computational morphometrics

Compared hallucinators to non-hallucinators

Whole-brain

41

31

Talairach

Correlations with total score of SAPS hallucination scale

Gaser et al. [31] (2004)

SPM99 Deformation-based morphometry

Compared hallucinators to non-hallucinators

Whole-brain

29

56

Talairach

Correlations with total score on items 1–3 of SAPSa

Neckel-mann et al. [60] (2006)

SPM99

Correlations with BPRS item 12

Whole-brain

12

N/A

MNI

O’Daly et al. [61] (2007)

Computational morphometrics

Correlations with BPRS item 12

Removed cerebellum & diencephalon

28

N/A

Talairach

García-Martí et al. [62] (2008)

SPM2

Correlations with PSYRATS-AHRS

Whole-brain

18

N/A

MNI

Nenadic et al. [63] (2010)

SPM2

Correlations with total score on items 1–3 of SAPS (included all 99 participants)

Whole-brain

38

61

MNI

van Tol et al. [64] (2014)

SPM8

Compared hallucinators to non-hallucinators

Whole-brain

31

20

MNI

Cierpka et al. [39] (2017)

SPM8

Compared hallucinators to non-hallucinators

ROI

10

10

MNI

Correlations with PANSS-P item 3b, BPRS item 12b and total score of PSYRATS-AHRSb

  1. SPM statistical parametric mapping, SAPS scale for the assessment of positive symptoms, BPRS brief psychiatric rating scale, PSYRATS—AHRS psychotic symptom rating scales—auditory hallucinations rating scale, PANSS-P positive and negative syndrome scale—Positive scale, ROI regions of interest, N/A not applicable, MNI Montreal Neurological Institute.
  2. aFindings of this correlation analysis were not included in the meta-analysis because the sample overlaps with that of Nenadic et al. [63].
  3. bFindings of this correlation analysis were not included in the meta-analysis because no coordinates were provided.