Table 1 Correlations of human regional T1/T2-weighted myelin estimates to sub-components of the Clinician Administered PTSD Scale (CAPS).

From: Regional gray matter oligodendrocyte- and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans

 

Hippocampus

Amygdala

Corpus callosum

Total CAPS

0.38*

0.36*

0.15

Avoidance subscore

0.39*

0.40*

0.20

 Avoidance of thoughts, feelings, conversations

0.27

0.39*

0.09

 Avoidance of activities, places, people

0.38*

0.30

0.16

 Inability to recall aspects of trauma

0.07

0.20

0.04

 Diminished interest in activities

0.33*

0.35*

0.16

 Detachment or estrangement

0.20

0.14

0.09

 Restricted affect

0.39*

0.24

0.25

 Sense of foreshortened future

0.26

0.29

0.20

Re-experiencing subscore

0.25

0.30

0.11

 Intrusive recollection

0.04

0.06

0.09

 Distressing dreams

0.26

0.22

0.02

 Flashbacks

0.01

0.06

0.15

 Psychological distress at exposure to cues

0.29

0.52**

0.15

 Physiological distress at exposure to cues

0.20

0.38*

0.18

Hyperarousal subscore

0.48**

0.38*

0.15

 Difficulty sleeping

0.45**

0.31

0.12

 Irritability, frequency

0.56**

0.28

0.06

 Difficulty concentrating

0.35*

0.29

0.05

 Hypervigilance

0.15

0.17

0.03

 Exaggerated startle response

0.26

0.33*

0.03

  1. T1w/T2w ratios were measured from 38 trauma-exposed male veterans, as described in Chao et al., 2015. In all, 19 trauma-exposed veterans were diagnosed with PTSD, while 19 were without PTSD. All analyses are Spearman’s rank-order correlations (*ρ < 0.05, **ρ < 0.01).
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