Fig. 6: Sex-stratified GR-response eSNP associations with psychiatric disorders.
A Bar plot of enrichment results for GR-response tag eSNPs and GWAS SNPs. The black indicates a fold enrichment at 1 and a star indicates a permutation-based FDR < 0.05. AD = Alzheimer’s disease, ADHD = attention-deficit/hyperactivity disorder, AUT = autism spectrum disorders, BP = bipolar disorder, Cross = cross disorder analysis, EA = educational attainment, MDD = major depressive disorder, PTSD = post-traumatic stress disorder, SCZ = schizophrenia, T2D = diabetes type 2, TS = Tourette syndrome. B Association between residualized female TSPSs and standardized scores of severity of depressive symptoms computed in LMU cohort (girls: β = −7.98 × 10−4, SE = 4.04 × 10−4, p-value = 0.0496; boys: β = 1.12 × 10−3, SE = 8.3 × 10−4, p-value = 0.18).
