Fig. 3: Equilibrium quality evaluation/inspection represented by regional cerebral uptake of [C]ABP688 expressed as distribution volume referenced to plasma parent, V.

a Normalized-range variations of the VT values in the plateau range (30–60 min) for the motor cortex and cerebellum GM-control regions during the equilibrium phase. The plasma parent compound normalized activity-concentration range for evaluating the equilibrium quality is also shown. b Average VT curves and the linear regression applied to the data plateau range (30–60 min) for the slope analysis. SE = standard error of the mean (mean/\(\sqrt n\)), where n = sample size.