Fig. 4: Task effect results shown by the regional and voxel-wise cerebral uptake of [C]ABP688 expressed as distribution volume referenced to cerebellum grey matter, BP.

a BPND curves for the anatomical and functional brain regions analyzed. Significant effects can be seen in the healthy group. The red line marks the start point of tracer equilibrium phase. After 30 min, the first two time points represent RS1 and the remaining three time points represent the MMN task moments (MMN1, MMN2, and MMN3). b BPND parametric images for the group average per acquisition moment.