Fig. 3: ddPCR measurements in brain regions and age groups.
From: Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain
A Expression of the M-L splice form, TSS1 and TSS2 with ddPCR on the case-control sample set. Molecules per μL normalised to GUSB (log2-scale). Statistical testing with ANOVA and Tukey’s honestly significant difference (HSD) post-hoc test (**** p < 0.0001, ** p < 0.02). B Boxplot of ddPCR measurements of the M-L splice variant, TSS1 and TSS2 in the child-development set. Samples have been grouped into below and above 10 years old. Molecules per μL normalised to GUSB (log2-scale). t-tests of the difference in mean between age groups with unadjusted p-values for each target are indicated. C ddPCR measurements of the M-L splice variant, TSS1 and TSS2 in the case-control sample set, showing all tissues and diagnostic group. Molecules per μL normalised to GUSB (log2-scale).
