Fig. 2: Global miRNA association study of cognitive trajectory in ROS/MAP. | Translational Psychiatry

Fig. 2: Global miRNA association study of cognitive trajectory in ROS/MAP.

From: Brain microRNAs are associated with variation in cognitive trajectory in advanced age

Fig. 2

A Volcano plot of the global miRNA association study of cognitive trajectory in the discovery dataset. The miRNAs colored in blue are those associated with cognitive trajectory at adjusted p < 0.05. B Volcano plot for the meta-analysis of the global miRNA association studies of cognitive trajectory in the discovery and replication datasets. C Plot of slope of cognitive trajectory versus individual miR-132 and miR-29a expression in the discovery dataset. Note that the more positive the slope, the more stable the trajectory, and the more negative the slope, the faster the decline.

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