Fig. 3: Percent variance of cognitive trajectory explained by miR-132 and miR-29a.
From: Brain microRNAs are associated with variation in cognitive trajectory in advanced age
This figure shows the percent variance of cognitive trajectory explained by variables in the model. A Percent variance of cognitive trajectory explained by miR-132, miR-29a, and each of the eight considered pathologies (amyloid density, tangle density, Lewy bodies, macroinfarct, microinfarcts, atherosclerosis, cerebral amyloid angiopathy, and hippocampal sclerosis), B Percent variance of cognitive trajectory explained by miR-132 and miR-29a after effects of the eight cerebral pathologies have been regressed out. For all analyses, the effects of sex, age at death, PMI, RIN, study, and proportions of neurons, astrocytes, oligodendrocytes, and microglia have been regressed out in these percent variance estimates.
