Table 2 Gene and RNA editing variants identified by RNA-Seq between depressed patients (DEP, n = 26) and controls (CTRL, n = 31) in the discovery cohort.
From: A game changer for bipolar disorder diagnosis using RNA editing-based biomarkers
Ensembl ID | GeneName | Region | Chr | Position (GRCh38) | Coverage | Editing CTRL | Editing DEP | Fold change | Fold median | P value | AUC ROC |
|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000183049 | CAMK1D | intron | 10 | 12378385 | 46 | 17 | 21 | 1.28 | 1.33 | 2.20E–03 | 0.796 |
ENSG00000033327 | GAB2 | intron | 11 | 78330944 | 37 | 17 | 24 | 1.43 | 1.52 | 3.71E–03 | 0.896 |
ENSG00000142166 | IFNAR1 | 3UTR | 21 | 33355807 | 32 | 17 | 24 | 1.42 | 1.24 | 1.21E–02 | 0.910 |
ENSG00000157551 | KCNJ15 | intron | 21 | 38287526 | 85 | 22 | 18 | 0.83 | 0.75 | 1.85E–02 | 0.737 |
ENSG00000166501 | LYN | 3UTR | 8 | 56012553 | 44 | 15 | 20 | 1.35 | 1.33 | 4.37E–03 | 0.774 |
ENSG00000135679 | MDM2 | intron | 12 | 68821612 | 36 | 12 | 16 | 1.29 | 1.29 | 2.89E–02 | 0.797 |
ENSG00000166501 | PRKCB | intron | 16 | 23920896 | 78 | 16 | 12 | 0.74 | 0.69 | 3.43E–03 | 0.853 |
