Table 2 Overview of the number of differentially methylated CpG sites in different group comparisons.

From: Maternal prenatal depressive symptoms and toddler behavior: an umbilical cord blood epigenome-wide association study

		Whole								Female								Male
		All				SSRI-treatment excluded				All				SSRI-treatment excluded				All				SSRI-treatment excluded
Group 1	Group 2	n1	n2	pa	pu	n1	n2	pa	pu	n1	n2	pa	pu	n1	n2	pa	pu	n1	n2	pa	pu	n1	n2	pa	pu
High int	Low int	132	115	0	47,111	128	112	0	47,505	70	59	0	34,518	67	58	0	34,590	62	56	0	47,403	61	54	0	46,870
HC-High int	HC-Low int	89	92	0	40,165	89	92	0	40,506	43	49	0	33,980	43	49	0	33,361	46	43	0	39,394	46	43	0	40,542
HC-High int	PND-High int	89	43	0	44,070	89	39	0	41,104	43	27	0	35,021	43	24	0	33,855	46	16	0	44,308	46	15	0	42,135
HC-High int	PND-Low int	89	23	0	71,787	89	20	0	67,190	43	10	0	42,357	43	9	0	39,869	46	13	0	47,373	46	11	0	45,661
HC-Low int	PND-High int	92	43	0	37,819	92	39	0	37534	49	27	0	33217	49	24	0	33340	43	16	0	44808	43	15	0	42288
HC-Low int	PND-Low int	92	23	0	51,457	92	20	0	49,173	49	10	0	38,283	49	9	0	37,605	43	13	0	38,183	43	11	0	36,319
PND-High int	PND-Low int	43	23	0	50,610	39	20	0	52,091	27	10	0	36,241	24	9	0	37,936	16	13	1	49,576	15	11	0	45,477
Hight ext	Low ext	134	97	0	37,800	128	95	0	38,268	64	58	0	43,770	60	58	0	41,719	70	39	0	39,338	68	37	0	40,561
HC-High ext	HC-Low ext	85	80	0	44,378	85	80	0	44,866	37	49	0	40,449	37	49	0	40,883	48	31	1	46,230	48	31	1	46,992
HC-High ext	PND-High ext	85	49	0	69,903	85	43	0	59,957	37	27	0	53,075	37	23	0	44,726	48	22	0	50,427	48	20	0	46,387
HC-High ext	PND-Low ext	85	17	0	37,679	85	15	0	35,903	37	9	0	39,569	37	9	0	38,231	48	8	0	38,968	48	6	0	35,516
HC-Low ext	PND-High ext	80	49	0	50,085	80	43	0	44,444	49	27	0	48,901	49	23	0	42,005	31	22	0	36,059	31	20	0	35,834
HC-Low ext	PND-Low ext	80	17	0	42,682	80	15	0	40,010	49	9	1	40,581	49	9	0	37,974	31	8	0	38,662	31	6	0	35,611
PND-High ext	PND-Low ext	49	17	1	48,940	43	15	1	45,621	27	9	0	60,152	23	9	0	49,011	22	8	0	40,102	20	6	0	37,058
High tot	Low tot	136	100	0	37,124	132	97	0	37,850	67	54	0	37,030	64	54	0	35,779	69	46	0	44,327	68	43	0	41,705
HC-High tot	HC-Low tot	89	83	0	42,788	89	83	0	43,490	41	45	0	33,911	41	45	0	34,068	48	38	0	43,278	48	38	0	43,599
HC-High tot	PND-High tot	89	47	0	62,034	89	43	0	55,409	41	26	0	42,880	41	23	0	38,093	48	21	0	46,215	48	20	0	45,373
HC-High tot	PND-Low tot	89	17	0	42,263	89	14	0	35,599	41	9	0	35,517	41	9	0	35,286	48	8	0	41,582	48	5	0	29,787
HC-Low tot	PND-High tot	83	47	0	42,190	83	43	0	39,766	45	26	0	41,780	45	23	0	37,415	38	21	0	40,619	38	20	0	40,074
HC-Low tot	PND-Low tot	83	17	0	37,405	83	14	0	32,964	45	9	0	35,391	45	9	0	34,694	38	8	0	34,688	38	5	0	27,956
PND-High tot	PND-Low tot	47	17	0	36,532	43	14	0	35,418	26	9	0	43,518	23	9	0	39,456	21	8	0	39,232	20	5	0	32,099

PND Prenatal depressive symptoms, HC healthy control, int internalizing scores, ext externalizing scores, tot total scores, pa Number of CpGs significant with p value adjusted for multiple testing and for sample plate, sentrix position, granulocytes, nucleated red blood cells, cd8t-cells, age at partus, pre-pregnancy BMI, maternal place of birth, parity, gestational age, delivery mode and education, pu Number of CpGs significant with an unadjusted p value.

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Table 2 Overview of the number of differentially methylated CpG sites in different group comparisons.

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