Table 3 Pearson correlation estimates and p-values for the association between pre- to post-treatment change in 8-oxodG (Δ8-oxodG) and 8-oxoGuo (Δ8-oxoGuo), respectively, vs. pre- to post-treatment change in the predictor variables depressive symptoms (ΔHAM-D6, ΔHAM-D17), body mass index (ΔBMI), area under the curve of salivary cortisol excretion (full-day profile) (ΔAUCfull), high-sensitivity c-reactive protein (ΔhsCRP), and post-treatment plasma escitalopram concentration.

From: Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression

 

ΔHAM-D6

ΔHAM-D17

ΔBMI

ΔAUCfull

ΔhsCRP

p-escitalopram

Δ 8-oxodG

0.15

p = 0.21

0.15

p = 0.18

−0.14

p = 0.21

−0.30

p = 0.0497

−0.04

p = 0.74

0.006

p = 0.96

Δ 8-oxoGuo

0.15

p = 0.20

0.15

p = 0.21

−0.03

p = 0.77

−0.49

p = 0.0009

−0.16

P = 0.16

0.24

p = 0.051

  1. Significant associations are in bold.
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