Fig. 1: Joint swelling and depression-like phenotypes after collagen-induced arthritis. | Translational Psychiatry

Fig. 1: Joint swelling and depression-like phenotypes after collagen-induced arthritis.

From: Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation

Fig. 1

A Schedule of treatment, behavioral tests and sample collection. B Body weight among two groups (repeated measure one-way ANOVA, F1,18 = 22.988. P < 0.001). C Representative images of wrist joint and representative H&E staining on the knee joint. D Clinical score (repeated measure one-way ANOVA, F1,18 = 34.892. P < 0.001). E Locomotion test (LMT) (Student t-test: t = 0.701, P = 0.492). F TST (Student t-test: t = −2.843, P = 0.011). G FST (Student t-test: t = −3.225, P = 0.005). H SPT (Student t-test: t = 2.831, P = 0.011). I Plasma TNF-α levels (Student t-test: t = −0.446, P = 0.661). J Plasma IL-6 levels (Student t-test: t = −4.127, P < 0.001). K PSD-95 (Student t-test: t = 2.138, P = 0.046). L GluA1 (Student t-test: t = 2.204, P = 0.045). Data are shown as mean ± S.E.M. (n = 10). *P < 0.05, **P < 0.01, ***P < 0.001.

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