Table 1 Information on meta-analyses included in the umbrella review.
From: Genetics of autism spectrum disorder: an umbrella review of systematic reviews and meta-analyses
Genes | Studies | Study design | HWE check | AMSTAR |
|---|---|---|---|---|
CNTNAP2 | Uddin et al. [44] | case control | Yes | 5 |
CNTNAP2 | Wang et al. [43] | case control | – | 5 |
CNTNAP2 | Werling et al. [41] | case control&family based | – | 3 |
CNTNAP2 | Zhang et al. [42] | case control&family based | – | 5 |
COMT | Yang et al. [39] | case control | Yes | 6 |
GABRB3 | Mahdavi et al. [51] | case control | Yes | 5 |
GABRB3 | Noroozi et al. [52] | case control | Yes | 5 |
MTHFR | Li et al. [33] | case control | Yes | 5 |
MTHFR | Li et al. [34] | case control | Yes | 5 |
MTHFR | Pu et al. [29] | case control | Yes | 5 |
MTHFR | Rai [30] | case control | Yes | 3 |
MTHFR | Razi et al. [32] | case control | Yes | 6 |
MTHFR | Sadeghiyeh et al. [31] | case control | Yes | 5 |
MTHFR | Wang and Wu [35] | case control | Yes | 6 |
MTHFR | Zhanget al. [36] | case control | Yes | 6 |
OXTR | Kranz et al. [46] | family based | – | 2 |
OXTR | LoParo and Waldman [45] | case control&family based | – | 5 |
OXTR | Zhou [47] | case control | – | 6 |
RELN | Chen [49] | case control | – | 4 |
RELN | Hernández-GarcÃa (2020) [50] | case control | – | 3 |
RELN | Wang [48] | case control&family based | Yes | 5 |
SLC25A12 | Aoki and Cortese [53] | case control&family based | – | 4 |
SLC25A12 | Liu et al. [54] | case control&family based | Yes | 7 |
SLC6A4 | Huang and Santangelo [37] | family based | Yes | 5 |
SLC6A4 | Mo et al. [38] | case control&family based | – | 5 |
SLC6A4 | Wang et al. [40] | case control | – | 6 |
SLC6A4 | Yang et al. [39] | case control&family based | Yes | 6 |
VDR | Sun [55] | case control | Yes | 6 |
VDR | Yang and Wu [56] | case control | Yes | 5 |
