Fig. 1: TGMV and IQ in HSV1+ and HSV1− patients with SMI and HC.
From: Herpes simplex virus 1 infection on grey matter and general intelligence in severe mental illness
Left: Total grey matter volume (TGMV) in mm3 in herpes simplex virus 1 (HSV1) immunoglobulin G (IgG) seropositive (HSV1+) and seronegative (HSV1−) patients with severe mental illness (SMI) and healthy controls (HC). Right: Intelligent quotient (IQ) in HSV1 + and HSV1− patients with SMI and HC. HSV1+ patients had significantly smaller TGMV and lower IQ compared with HSV1− patients, whereas no such differences were found between HSV1+ and HSV1− HC. 420 patients (223 HSV1−/197 HSV1+) and 481 HC (264 HSV1− and 217 HSV1+) were included in both analyses. Adjusted means with 95% confidence intervals are shown *p < 0.05.
