Fig. 3: EEG parameters as predictive biomarkers. | Translational Psychiatry

Fig. 3: EEG parameters as predictive biomarkers.

From: Quantitative electroencephalography parameters as neurophysiological biomarkers of schizophrenia-related deficits: A Phase II substudy of patients treated with iclepertin (BI 425809)

Fig. 3

Spearman correlation of EEG parameters at baseline with CfB in clinical assessments in the combined 10 + 25 mg dose groups (A) and placebo group (B). + Correlation coefficient ≥0.3 and p < 0.05; − correlation coefficient ≤ −0.3 and p < 0.05. ASSR auditory steady-state response, CfB change from baseline, EEG electroencephalography, LNS letter-number span, MATRICS Measurement and Treatment Research to Improve Cognition in Schizophrenia, MCCB MATRICS Consensus Cognitive Battery, MMN mismatch negativity, NAB neuropsychological assessment battery, PANSS positive and negative syndrome scale, PLF phase-locking factor, TMT-A Trail Making Test Part A, WMS-III SS Wechsler Memory Scale 3rd edition, spatial span.

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