Fig. 1: Manhattan plot from the GWAS of PTSD cases in the CCSS cohort, showing the top variants in 10 independent risk loci. | Translational Psychiatry

Fig. 1: Manhattan plot from the GWAS of PTSD cases in the CCSS cohort, showing the top variants in 10 independent risk loci.

From: Genome-wide association study of posttraumatic stress disorder among childhood cancer survivors: results from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort

Fig. 1: Manhattan plot from the GWAS of PTSD cases in the CCSS cohort, showing the top variants in 10 independent risk loci.

CCSS Childhood Cancer Survivor Study, GWAS genome-wide association study, PTSD posttraumatic stress disorder. This analysis included 671 cases and 3313 controls. Single-nucleotide polymorphisms in green are in linkage disequilibrium (r2 < 0.1) with the index single-nucleotide polymorphisms (diamonds) and have a P-value < 0.001. Index variants located with a distance less than 400 kilobase are considered as 1 locus. The model was adjusted for sex and top 10 principal components. The point estimates are provided in Table 2 and Supplementary Table 2.

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