Fig. 2: Polygenic associations between common psychosocial traits and PTSD in childhood cancer survivors. | Translational Psychiatry

Fig. 2: Polygenic associations between common psychosocial traits and PTSD in childhood cancer survivors.

From: Genome-wide association study of posttraumatic stress disorder among childhood cancer survivors: results from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort

Fig. 2: Polygenic associations between common psychosocial traits and PTSD in childhood cancer survivors.

iPSYCH The Lundbeck Foundation Initiative for Integrative Psychiatric Research, PGC Psychiatric Genomics Consortium, PTSD posttraumatic stress disorder. We performed polygenic risk score (PRS) analyses using genetic variants of P-value < 0.005 from corresponding GWASs of psychosocial traits. Odds ratios (per 1 standard deviation of standardized PRS) of PTSD in cancer survivors are shown as x-axis, while error bars indicate 95% confidence intervals. Pink bars denote significant associations (P-value < 0.05).

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