Fig. 2: Visually oriented brain-based markers of early psychosis.
From: Visual system assessment for predicting a transition to psychosis
A Visual thalamo-cortical hyperconnectivity occurs in schizophrenia patients relative to HCs (Figure panel shows the thalamic seed; adapted with permission from [58]). B Similar hyperconnectivity patterns have been observed in CHR patients who convert versus those who do not convert to a psychotic disorder (Adapated with permission from [61]). C Different investigators have found comparable patterns (after FDR correction) in early-stage non-affective psychosis patients relative to HCs, with one-third of the visual nodes being hyperconnected to the thalamic node (Adapted with permission from [60]). D Briefly flashed checkered images have elicited a muted P1 amplitude in FEPs relative to HCs (Adapted with permission from [65]). E, F During a change-in-motion detection task, gamma band activity within ten occipital regions was smallest in FEP subjects, intermediate in CHR patients, and greatest in psychiatric patients not meeting CHR criteria (non-CHR) (Adapted with permission from [68]).
