Table 1 Sociodemographic and clinical characteristics of the total sample.

Age

31.67 ± 12.93

38.79 ± 13.84

0.054^c

36.48 ± 14.10

0.161^c

Sex (f/m)

12/9

24/18

0.999^d

39/24

0.296^d

Verbal IQ_MWT-B

111.00 ± 11.91

115.24 ± 13.59

0.230^c

115.68 ± 14.69

0.398^c

Scanner Settings (MR-BCpre, MR-BCpost, MS)

11/0/10

22/5/15

0.223^d

35/1/27

0.114^d

Smoking status (yes/no) (n = 125)

7/13

12/30

0.608^d

7/56

0.023^d

HDRS total score (n = 125)

8.40 ± 6.82

4.36 ± 4.51

0.034^e

1.37 ± 1.99

<0.001^f

Medication Load Index

1.33 ± 1.74

0.79 ± 1.07

0.116^e

n/a

n/a

Psychiatric comorbidities (yes/no)

4/17

5/37

0.445^d

n/a

n/a

CTQ total score

43.60 ± 11.83

40.40 ± 12.55

0.246^e

31.95 ± 8.59

<0.001^f

Familial risk for mood disorder (yes/no)

7/14

18/24

0.466^d

8/55

0.002^d

Remission status (acute/remitted)

14/7

19/23

0.108^d

n/a

n/a

Time since first depressive symptoms (weeks)

63.43 ± 99.83

50.57 ± 63.08

0.605^e

n/a

n/a

Duration of index episode (months) (n = 52)

13.68 ± 15.87

14.06 ± 13.24

0.960^e

n/a

n/a

Psychiatric hospitalization at index episode (yes/no)

16/5

21/21

0.047^d

n/a

n/a

Smoking status (yes/no) (n = 120)

5/14

12/29

0.813^d

8/52

0.125^d

Body coil/site (BCpre, BCpost, Münster)

0/11/10

0/27/15

0.363^d

0/36/27

0.622^d

Interscan interval (months)

63.28 ± 3.12

65.04 ± 5.32

0.336^e

63.34 ± 5.44

0.052^f

HDRS total score

6.62 ± 5.90

2.55 ± 2.75

0.004^e

1.25 ± 1.78

<0.001^f

Medication Load Index

0.86 ± 1.11

0.36 ± 0.82

0.015^e

n/a

n/a

Remission status (acute/remitted)

11/10

0/42

<0.001^d

n/a

n/a

Number of depressive episodes during follow-up

1.48 ± 0.81

n/a

n/a

n/a

n/a

Duration of depressive episodes during follow-up (months)

6.49 ± 4.62

n/a

<0.001^e

n/a

n/a

Rehospitalization during follow-up (yes/no)

9/12

0/42

<0.001^d

n/a

n/a