Table 1 Demographic and neuropsychological information of study participants.

From: The neurophysiological effect of NMDA-R antagonism of frontotemporal lobar degeneration is conditional on individual GABA concentration

 

CON

bvFTD/PSP

CON vs. bvFTD/PSP

 

M (SD)

p-val (Bayes Factor)

n

19

20

 

Sex

M14:F5

M18:2

n.s

Age

67.05 (4.72)

64.95 (8.49)

n.s (0.45)

Neuropsychology

MMSE

29.63 (0.50)

26.9 (2.2)

*** (2598.18)

ACE-R

 Total

96.63 (2.54)

80.2 (11.03)

*** (48.52e+3)

 Attention

17.89 (0.32)

16.95 (1.36)

** (8.09)

 Memory

24.58 (1.47)

21 (4.22)

** (26.37)

 Verbal Fluency

12.74 (1.52)

5.7 (3.4)

*** (1.07e+7)

 Language

25.63 (0.83)

23.55 (2.19)

*** (65.86)

 Visuospatial

15.79 (0.41)

13 (3.54)

** (21.43)

INECO

 Total

25.13 (2.23)

16.71 (5.4)

*** (26.52e+3)

FAB Total

17.16 (1.07)

13.32 (3.68)

*** (212.19)

Hayling

 Overall Scaled score

5.95 (0.85)

2.65 (2.01)

*** (10.89e+4)

Graded—naming total

25.47 (2.91)

17.68 (5.13)

*** (8.72e+e)

FRS Total (Logit)

4.23 (1.27)

−0.89 (2.26)

*** (1.16e+7)

CBI-R

 Total

5.67 (6.03)

68.32 (34.29)

*** (1.35e+6)

 Memory and orientation

2.06 (2.16)

10.42 (7.23)

*** (492.72)

 Everyday skills

0 (0)

8.74 (6.55)

n/a

 Self-care

0 (0)

4.21 (4.76)

n/a

 Abnormal behaviour

0.72 (1.02)

8.89 (8.18)

*** (134.55)

 Mood

0.67 (1.14)

4.05 (3.01)

*** (269.54)

 Beliefs

0 (0)

1.42 (1.8)

n/a

 Eating habits

0.17 (0.38)

6.79 (4.96)

*** (5893.82)

Sleep

0.89 (1.23)

4.11 (2.72)

*** (331.85)

 Stereotypic and motor

0.83 (1.15)

8.21 (5.72)

*** (2872.15)

 Motivation

0.33 (0.69)

12.11 (5.52)

*** (4.72e+7)

  1. n/a—variance in controls were equal to zero, violating assumption of equality of variances.
  2. *p < 0.05.
  3. **p < 0.01.
  4. ***p < 0.001, uncorrected.
  5. bvFTD behavioural variant frontotemporal dementia, CON controls, PSP progressive supranuclear palsy,
  6. BF Bayes Factor, Conventional thresholds for Bayes Factors represent substantial (>3), strong (>10) and very strong (>30) evidence in favour of alternate hypothesis.
  7. ACE-R Addenbrooke's Cognitive Examination-Revised, CBI-R Cambridge Behavioural Inventory Revised, FAB frontal assessment battery, FRS Frontotemporal Dementia Rating Scale, MMSE mini-mental state exam.