Fig. 2: Effect of single- and multiple-dose oxytocin treatment on amygdala BOLD signal amplitude. | Translational Psychiatry

Fig. 2: Effect of single- and multiple-dose oxytocin treatment on amygdala BOLD signal amplitude.

From: Effects of single- and multiple-dose oxytocin treatment on amygdala low-frequency BOLD fluctuations and BOLD spectral dynamics in autism

Fig. 2: Effect of single- and multiple-dose oxytocin treatment on amygdala BOLD signal amplitude.

A Mean changes-from-baseline in the fractional amplitude of low-frequency fluctuations (fALFF) are visualized separately for each treatment group (oxytocin, placebo), assessment session (single-dose, multiple-dose), and amygdala region (right, left). Data are visualized and averaged across BOLD components 1 and 2. Both after a single-dose and after multiple-dose treatment, the oxytocin group displayed significantly lower amygdalar fALFF, compared to the placebo group. Vertical bars denote ± standard errors. B Visualization of the brain-behavior relationship between multiple-dose changes-from-baseline in self-reported feelings of tension (assessed with the Profile of Mood Scale) and multiple-dose changes-from-baseline in fALFF (averaged across amygdala regions and BOLD components).

Back to article page