Fig. 4: Longitudinal models of polygenic associations with alcohol use and misuse. | Translational Psychiatry

Fig. 4: Longitudinal models of polygenic associations with alcohol use and misuse.

From: Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk

Fig. 4

Predicted values for alcohol use index (AUI) from ages 12 to 32 using linear mixed models in Add Health (N = 5107). Values for EXT and ALCP-specific polygenic scores set to ±1.5 SD. The shaded areas represent 95% confidence intervals. Confidence intervals estimated using percentile method bootstrapping over 1000 bootstrap samples. All other covariates set to mean values.

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