Fig. 1: Il18−/− mice showed behavioral changes after stress. | Translational Psychiatry

Fig. 1: Il18−/− mice showed behavioral changes after stress.

From: Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Fig. 1: Il18−/− mice showed behavioral changes after stress.

A The body weights of each group before stress treatment, after treatment, and before behavioral tests are shown. The behavioral tests results, including the open field test (B), forced swim test (C), and tail suspension test (D), are shown. B The graph shows the distance traveled by each mouse during 2 min in the open field test. C In the forced swim test, stressed Il18−/− mice had a longer swimming distance (left) and less immobility time (left) than those of non-stressed mice, and these phenotypes were not observed in Il18+/+ mice. D In the tail suspension test, stressed Il18−/− mice showed a decreased immobility time, similar to the forced swim test. *p < 0.05 (stressed Il18−/− mice versus non-stressed mice), (n = 12 per group).

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