Fig. 5: Intracerebral injection of IL18 partially improved behavioral changes in stressed Il18−/− mice. | Translational Psychiatry

Fig. 5: Intracerebral injection of IL18 partially improved behavioral changes in stressed Il18−/− mice.

From: Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice

Fig. 5: Intracerebral injection of IL18 partially improved behavioral changes in stressed Il18−/− mice.

A The body weights of each group before intracerebral injection of IL18, before stress treatment, after treatment, and before behavioral tests are shown. The behavioral tests results, including the open field test (B), tail suspension test (C), and forced swim test (D), are shown. B The graph shows the distance traveled by each mouse during 2 min (left) and the total distance (right) traveled in the open field test. C In the tail suspension test, a significant difference was found only during the first min. D In the forced swim test, no significant difference was observed. *p < 0.05 (stressed Il18−/− mice with IL18 administration versus the other groups), (n = 12 per group).

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