Fig. 1: Behavioural assessment of Sapap3−/− mice. | Translational Psychiatry

Fig. 1: Behavioural assessment of Sapap3−/− mice.

From: The Sapap3−/− mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviours

Fig. 1

A Photographs of custom-made apparatus for behavioural assessment, consisting of four acrylic chambers, each equipped with top and side cameras, connected to a digital video-recording system. B Detailed graphic illustration of a single video chamber with ad libitum water and food access. C Time scale of behavioural assessment. Mice were video-recorded in the behavioural apparatus for 24 h. Four intermittent time bins of 30 min each (i.e., a total of 2 h) were manually analysed offline for repetitive behaviours including self-grooming, head-body twitches and hindpaw scratching. The scored time bins were distributed regularly across the light/dark circadian following previous protocols (Welch et al., 2007).

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