Fig. 4: Excessive head/body twitches, scratching and short grooming events are associated in Sapap3−/− mice. | Translational Psychiatry

Fig. 4: Excessive head/body twitches, scratching and short grooming events are associated in Sapap3−/− mice.

From: The Sapap3−/− mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviours

Fig. 4

A The proportion of novel detected repetitive behaviours in Sapap3−/− mice outweighs previously reported syntactic self-grooming behaviour (Pearson’s χ2 test, p < 0.0001). B Head/body twitches positively correlate with short, single-phase grooming but not long, syntactic grooming bouts in Sapap3−/− mice (Spearman correlation, p < 0.05, p = ns, respectively). C Scratching bouts also correlate positively with short, single-phase grooming but not long, syntactic grooming bouts in Sapap3−/− mice (Spearman correlation, p < 0.01, p = ns, respectively). Correlation estimates are plotted in a grey solid line or a dotted black line for wildtype or Sapap3−/− mice (n = 9 animals per genotype), respectively.

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