Fig. 5: Effects of NAc DBS on anhedonia, alcohol craving and quality of life. | Translational Psychiatry

Fig. 5: Effects of NAc DBS on anhedonia, alcohol craving and quality of life.

From: Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial

Fig. 5: Effects of NAc DBS on anhedonia, alcohol craving and quality of life.The alt text for this image may have been generated using AI.

Depiction of median values and of significant longitudinal changes and group differences in A anhedonia (SHAPS), B, C alcohol craving (OCDS and AUQ), and D quality of life (WHOQOL-BREF) at baseline, at the 6-month visit (i.e., end of blinded phase), and at 18 months (after all patients had been actively stimulated for at least 12 months). *Significant differences between time points or study groups, as indicated, at p < 0.05, determined using Wilcoxon tests and Mann–Whitney U tests.

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