Fig. 1: Association between childhood maternal antipathy and neural activation to social reward anticipation.

Note. Whole-brain analyses indicated childhood maternal antipathy was associated with decreased activation during social reward anticipation in the ventromedial prefrontal cortex, bilateral anterior insula, and superior frontal sulcus. The four clusters survived corrections for multiple comparisons at P < 0.001, uncorrected and k > 320 corresponding to P < 0.05, FWE correction. The t-map of the regression analysis controlling for age, sex, years of education, general psychopathology, and psychotropic medication load was thresholded at P < 0.005 for displaying purposes and the color gradient depicts the respective t-values of the maternal antipathy regression weights.