Table 1 Sample characteristics.

From: Your smile won’t affect me: Association between childhood maternal antipathy and adult neural reward function in a transdiagnostic sample

Characteristic

Total (N = 118)

PTSD (n = 25)

MDD (n = 32)

SSD (n = 29)

HVs (n = 32)

Analysis

M

SD

M

SD

M

SD

M

SD

M

SD

F or χ2 or FET

Pa

Age (years)

31.1

11.0

33.0

10.8

31.3

12.0

31.9

12.7

28.8

8.5

0.74

0.530

Educational level (years)

12.3

1.4

12.2

1.5

12.5

1.2

11.9

1.6

12.6

1.2

1.66

0.181

Psychological assessments

 CECA.Q antipathy mother

21.26

9.46

25.00

9.57

22.78

8.43

18.07

8.69

19.72

10.10

3.12

0.029

 CECA.Q antipathy fatherb

22.90

9.17

24.32

10.24

24.81

8.70

20.50

8.73

21.87

8.90

1.38

0.251

 CECA.Q neglect from mother

17.18

7.91

21.20

9.17

17.09

6.87

16.17

8.63

15.03

6.18

3.27

0.024

 CECA.Q neglect from fatherb

23.19

8.74

26.68

9.82

22.06

7.07

23.15

9.85

21.52

7.95

1.92

0.130

 CECA.Q physical abuse by mother

0.94

1.58

1.00

1.53

0.69

1.38

0.83

1.65

1.25

1.76

0.74

0.532

 CECA.Q physical abuse by father

0.82

1.51

1.00

1.66

0.56

1.34

0.59

1.35

1.16

1.67

1.19

0.316

 CECA.Q sexual abuse

1.10

1.99

2.96

2.72

0.63

1.54

0.59

1.21

0.59

1.41

11.79

<0.001

 BSI Global Severity Index

0.92

0.66

1.25

0.69

1.40

0.52

0.74

0.41

0.33

0.36

29.81

<0.001

 PCL-5 sum score

22.40

18.81

41.72

13.38

27.63

19.39

14.14

12.15

9.56

11.15

27.72

<0.001

 BDI-II sum score

19.53

13.89

24.96

11.27

32.72

9.88

16.10

9.70

5.22

4.60

53.56

<0.001

 SSD-12 sum score

18.66

11.64

19.36

8.46

17.66

10.63

30.52

5.91

8.38

8.33

34.16

<0.001

 Psychotropic medication load

0.67

1.10

0.88

1.09

1.38

1.39

0.45

0.87

0

0

11.40

<0.001

fMRI task performance

 Hit rate (%)

66.02

6.79

63.89

8.04

66.93

6.39

65.76

6.59

67.01

6.18

1.26

0.290

 Reaction time (ms)

285.24

39.73

302.06

49.51

288.01

38.66

277.55

38.75

276.29

28.89

2.55

0.060

 Mean framewise displacement (mm)

0.12

0.08

0.12

0.10

0.12

0.09

0.12

0.07

0.11

0.07

0.06

0.979

 Bilateral VS activation to social reward anticipation

0.17

0.97

0.54

1.65

0.09

0.55

0.10

0.62

0.02

0.81

1.58

0.199

Characteristic

Total (N = 118)

PTSD (n = 25)

MDD (n = 32)

SSD (n = 29)

HVs (n = 32)

Analysis

N

%

N

%

N

%

N

%

N

%

F or χ2 or FET

Pa

Female

92

78.0

21

84.0

22

68.8

23

79.3

26

81.3

2.34c

0.504

Current medication

 Antidepressants

38

32.2

12

48.0

20

62.5

6

20.7

0

0

33.27c

<0.001

 Antipsychoticsd

5

4.2

2

8.0

3

9.4

0

0

0

0

4.89e

0.099

 Anticonvulsants

2

1.7

1

4.0

0

0

1

3.4

0

0

2.53e

0.351

Current DSM diagnosisf

 PTSD

27

22.9

25

100.0

2

6.3

0

0

0

0

  

 MDD

45

38.1

7

28.0

32

100.0

6

20.7

0

0

  

 SSD

32

27.1

2

8.0

1

3.1

29

100.0

0

0

  

 Anxiety disorders

15

12.7

4

16.0

8

25.0

3

10.3

0

0

  

 Eating disorders

6

5.1

3

12.0

2

6.3

1

3.4

0

0

  
  1. BDI-II Beck Depression Inventory revised, BSI Brief Symptom Inventory, CECA.Q Childhood Experience of Care and Abuse Questionnaire, FET Fisher’s exact test, HVs healthy volunteers, MDD major depressive disorder, PCL-5 PTSD Checklist for DSM-5, PTSD posttraumatic stress disorder, SSD somatic symptom disorder, SSD-12 Somatic Symptom Disorder–B-Criteria Scale.
  2. aUncorrected for multiple testing.
  3. bData are missing for five participants (1 MDD, 3 SSD, 1 HV) who indicated that they did not grow up with their father/surrogate father.
  4. cχ2 value.
  5. dSleep-inducing effect only.
  6. eFisher’s exact value.
  7. fParticipants were assigned to the group of individuals with PTSD, MDD, or SSD, if they were diagnosed with the respective disorder as first lifetime and current diagnosis at the time of study participation.
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