Fig. 5: Effects of repeated maternal separation (RMS) on regional brain volumes. | Translational Psychiatry

Fig. 5: Effects of repeated maternal separation (RMS) on regional brain volumes.

From: Early-life stress biases responding to negative feedback and increases amygdala volume and vulnerability to later-life stress

Fig. 5

Animals underwent MRI scanning on PND 20 (RMS n = 17, control n = 12), PND 62 (RMS n = 22, control n = 20), and PND 285 (RMS n = 21, control n = 23), and data were analyzed to quantify the volumes of six regions of interest. Maternal separation resulted in increased grey matter volume in the amygdala at the timepoint in late adulthood during adult stress, but not in early adulthood or immediately following RMS.

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