Fig. 1: Latent variable model for the association between 5-HT4R binding and neural responses during processing of emotional stimuli. | Translational Psychiatry

Fig. 1: Latent variable model for the association between 5-HT4R binding and neural responses during processing of emotional stimuli.

From: Association between brain serotonin 4 receptor binding and reactivity to emotional faces in depressed and healthy individuals

Fig. 1

Figure shows the estimated latent variable model for the association between 5-HT4R binding and neural responses to emotionally salient stimuli. The green ellipses represent the latent variables PETLV and fMRILV. The dashed lines between caudate and putamen represent additional shared correlation. Circular dashed lines represent error estimates included in the model. β reflects the parameter estimate for the association between the two latent variables. λ represents the loading of a given regional estimate onto its respective latent variable. Both PETLV and fMRILV were adjusted for age and sex, and PETLV was additionally adjusted for 5-HTTLPR polymorphism (5-HTTLPR) and weight-adjusted [11C]SB207145 injected mass (µg/kg) (Inj. Mass).

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