Fig. 1: Associations between change in depression and change in mean diffusivity as a function of treatment. | Translational Psychiatry

Fig. 1: Associations between change in depression and change in mean diffusivity as a function of treatment.

From: Rapid neuroplasticity changes and response to intravenous ketamine: a randomized controlled trial in treatment-resistant depression

Fig. 1

Within-group correlations between change in QIDS-SR (A, C, E) or MADRS (B, D, F) scores and the change in mean diffusivity for select brain regions. Post hoc Pearson r and p values shown separately for the vehicle (n = 31) and ketamine (n = 67) groups; see main text and Table 2 for full omnibus regression statistics. A positive change in depression score indicates an improvement in depression on that scale, and a positive change in MD indicates decreased diffusion in that region (interpreted as increased plasticity).

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