Fig. 1: Correlations between cerebrospinal fluid (CSF) and plasma concentrations of soluble biomarkers measured in the current study.

Correlations are shown for the full sample, and for subgroups of participants: people with HIV and Any Depressive Symptoms (maximum sample n = 33), people with HIV and No Depressive Symptoms (maximum sample n = 92), people without HIV and with Any Depressive Symptoms (maximum sample n = 9), and people without HIV and with No Depressive Symptoms (maximum sample n = 70). For correlations in the full sample, the strength of correlations are graded across a 3-point scale selected to range from the 5th and 95th percentiles of the correlation coefficients to optimise visual comparisons: −0.6 (in deep red), 0.0 (in light yellow), and +0.6 (in deep blue). For correlations in subgroups, the grading scale was: −1.0 (in deep red), 0.0 (in light yellow), and +1.0 (in deep blue).