Table 2 Summary of selected baseline characteristics and outcome data (PHQ-9 score/categories) by HIV status for participants from the COBRA cohort included in the current study.
Variable n (%) or median (interquartile range) | Overall N = 204 | Participants without HIV N = 79 | Participants with HIV N = 125 | p value |
|---|---|---|---|---|
General baseline characteristics | ||||
Study Site | 0.66 | |||
Amsterdam | 124 (60.8%) | 50 (63.3%) | 74 (59.2%) | |
London | 80 (39.2%) | 29 (36.7%) | 51 (40.8%) | |
Age (years) | 57 (51, 62) | 57 (52, 64) | 55 (51, 62) | 0.25 |
Sex at birth | >0.99 | |||
Female | 15 (7.4%) | 6 (7.6%) | 9 (7.2%) | |
Male | 189 (92.6%) | 73 (92.4%) | 116 (92.8%) | |
Men who have sex with men | 169 (82.8%) | 62 (78.5%) | 107 (85.6%) | 0.26 |
Ethnicity | 0.03 | |||
Black-African | 17 (8.3%) | 2 (2.5%) | 15 (12.0%) | |
White | 187 (91.7%) | 77 (97.5%) | 110 (88.0%) | |
Years of Education | 15 (13, 16) | 16 (14, 16) | 14 (13, 16) | 0.19 |
Current smoker | 58 (28.4%) | 20 (25.3%) | 38 (30.4%) | 0.53 |
Current alcohol use | 173 (84.8%) | 73 (92.4%) | 100 (80.0%) | 0.03 |
Use of recreational drugs in the past 6 months | 59 (28.9%) | 18 (22.8%) | 41 (32.8%) | 0.17 |
Ever injected drugs | 5 (2.5%) | 0 (0.0%) | 5 (4.0%) | 0.16 |
HIV-specific characteristics | ||||
Years since HIV diagnosis | 14.8 (9.0, 18.7) | |||
Currently on any form of combination antiretroviral therapy (cART) | 125 (100.0%) | |||
Duration of cART (years) | 11.9 (7.3, 15.5) | |||
HIV-RNA viral load <200 copies/mL | 125 (100.0%) | |||
Prior AIDS event | 40 (32.0%) | |||
Current CD4 + T-cell count (cells/µL) | 615 (472, 798) | |||
Nadir CD4 + T-cell count (cells/µL) | 180 (100, 250) | |||
PHQ-9 score | ||||
Total Score | 2 (0, 4) | 1 (0, 3) | 2 (1, 5) | 0.005 |
PHQ-9 > 4 (“Any Depressive Symptoms”) | 42 (20.6%) | 9 (11.4%) | 33 (26.4%) | 0.02 |
