Table 3 Association between EC values, PTSD status and WTC exposure duration.

From: Functional changes in neural mechanisms underlying post-traumatic stress disorder in World Trade Center responders

Parahippocampal Gyrus (anterior,right)

Amygdala (left)

Predictors

Estimates

CI

p

Predictors

Estimates

CI

p

Intercept

0.084

0.082–0.087

<0.001

Intercept

0.086

0.084–0.088

<0.001

Months on site

0.000

0–0.001

0.099

Months on site

0.000

0–0.001

0.492

Psychotropic

–0.002

0.005–0.002

0.307

Psychotropic

–0.002

0.005–0.000

0.063

Opioid

–0.002

0.008–0.005

0.576

Opioid

–0.008

0.014–0.003

0.001

MDD

–0.002

0.005–0.002

0.367

MDD

0.002

0.001–0.005

0.109

PTSD

0.007

0.003–0.011

<0.001

PTSD

0.005

0.002–0.008

0.001

Months on site*PTSD

–0.001

0.002–0.000

0.01

Months on site*PTSD

–0.001

0.001–0.000

0.005

Observations

86

Ā Ā Ā 

86

Ā Ā 

R2

0.162

Ā Ā Ā 

0.332

Ā Ā 
  1. Generalized linear regression models (GLM) examining WTC exposure duration (i.e., months on site) moderates the association between PTSD (WTC-PTSD versus non-PTSD) and EC values controlling for major depressive disorder (MDD) and medication use (psychotropic and opioid) on eigenvector centrality (EC) value of a single brain area (defined using the Harvard-Oxford atlas). P values are adjusted for multiple comparisons.