Table 3 The observational and genetic associations between BMI and life satisfaction in the CKB and UKB stratified by sex and urban and rural regions.
From: BMI and well-being in people of East Asian and European ancestry: a Mendelian randomisation study
Observational | Genetic | |||||
|---|---|---|---|---|---|---|
Study | Strata | Region | Beta (95% CI) per SD higher BMI | Pa | Beta (95% CI) per SD higher BMI | Pb |
CKB | All | Both | 0.058 (0.053, 0.063) | <1.00E-15 | −0.028 (−0.055, −0.002) | 0.04 |
Male | Both | 0.054 (0.047, 0.062) | <1.00E-15 | −0.077 (−0.123, −0.030) | 1.00E-03 | |
Female | Both | 0.062 (0.056, 0.069) | <1.00E-15 | −0.004 (−0.037, 0.028) | 0.80 | |
All | Urban only | 0.048 (0.041, 0.055) | <1.00E-15 | 0.006 (−0.036, 0.048) | 0.78 | |
Male | Urban only | 0.059 (0.048, 0.070) | <1.00E-15 | −0.033 (−0.109, 0.042) | 0.39 | |
Female | Urban only | 0.043 (0.034, 0.052) | <1.00E-15 | 0.024 (−0.027, 0.075) | 0.36 | |
All | Rural only | 0.066 (0.059, 0.072) | <1.00E-15 | −0.051 (−0.085, −0.016) | 4.00E-03 | |
Male | Rural only | 0.072 (0.062, 0.081) | <1.00E-15 | −0.103 (−0.162, −0.044) | 1.00E-03 | |
Female | Rural only | 0.063 (0.055, 0.072) | <1.00E-15 | −0.023 (−0.066, 0.019) | 0.28 | |
UKB | All | Both | −0.019 (−0.023, −0.014) | <1.00E-15 | −0.019 (−0.054, 0.016) | 0.28 |
Male | Both | −0.002 (−0.008, 0.005) | 0.65 | −0.003 (−0.049, 0.043) | 0.90 | |
Female | Both | −0.029 (−0.035, −0.023) | <1.00E-15 | −0.030 (−0.073, 0.014) | 0.19 | |
All | Urban only | −0.020 (−0.025, −0.015) | 2.3E-15 | −0.027 (−0.066, 0.011) | 0.16 | |
Male | Urban only | −0.005 (−0.013, 0.002) | 0.17 | −0.003 (−0.054, 0.048) | 0.90 | |
Female | Urban only | −0.028 (−0.035, −0.022) | <1.00E-15 | −0.031 (−0.079, 0.016) | 0.19 | |
All | Rural only | −0.013 (−0.024, −0.002) | 0.02 | 0.030 (−0.058, 0.119) | 0.50 | |
Male | Rural only | 0.015 (−0.002, 0.032) | 0.08 | 0.026 (−0.085, 0.137) | 0.64 | |
Female | Rural only | −0.030 (−0.045, −0.015) | 6.80E-05 | 0.010 (−0.111, 0.130) | 0.88 | |
