Fig. 5: Associations of childhood maltreatment (CTQ) and OXTR mRNA expression with OXTR DNA methylation at single CpG sites. | Translational Psychiatry

Fig. 5: Associations of childhood maltreatment (CTQ) and OXTR mRNA expression with OXTR DNA methylation at single CpG sites.

From: The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity

Fig. 5

Triangles depict the -log10 p-value of the association between DNA methylation and mRNA expression, circles depict the association with childhood maltreatment (CM) and filled squares indicate the differentially methylated positions (DMR) in association with CM. The dotted line indicates a nominal p-value of .05, whereas the solid line indicates an FDR of .05.

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