Fig. 3: Logistic regression analysis of main genetic variants, a summary of Odds Ratios, and 95% Confidence Intervals.

The bar graph displays the log odds ratios (OR) and their 95% confidence intervals (CI) for the main SNPs, haplotypes, and HLA (amino acid or classical alleles) based on the logistic regression analysis under both additive and dominant models. The vertical line represents the reference category. The horizontal bars represent the width of the 95% CI. The names of the variants are shown on the y-axis. The OR and p value are indicated on the right of the figure for each variant. As the p values of associations along odds ratio for the 3 tag SNPs haplotypes are comparable to that of the SNPs taken individually and since the 3 blocks of LD were not completely independent, we cannot conclude whether each variant by itself or their bearing haplotypes functionally drive ASD vulnerability.