Fig. 4: Specific effects of irradiation and lithium treatment on hNSPCs, for genes linked to neurogenesis. | Translational Psychiatry

Fig. 4: Specific effects of irradiation and lithium treatment on hNSPCs, for genes linked to neurogenesis.

From: Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors

Fig. 4

a Venn diagram of distribution of neurogenesis-linked demethylated gene promoters (5’ UTR) among treatment comparisons. b Bar graph depicting delta beta values for 14 neurogenesis-associated gene promoters (5’ UTR) corresponding to Li + IR vs IR. c Gene expression fold change compared to untreated and normalized to GAPDH, for GAD2 (n = 7). One-way ANOVA and paired t-test, *p < 0.05, **p < 0.005. Error bars represent mean and SD.

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